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fluorescent ac-devd-afc peptide substrate  (Bachem)

 
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    Structured Review

    Bachem fluorescent ac-devd-afc peptide substrate
    Fluorescent Ac Devd Afc Peptide Substrate, supplied by Bachem, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/fluorescent+ac-devd-afc+substrate/pm27889490-106-16-20?v=Bachem
    Average 90 stars, based on 1 article reviews
    fluorescent ac-devd-afc peptide substrate - by Bioz Stars, 2026-07
    90/100 stars

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    IRI-induced caspase activity. Cells were exposed to synergistic concentrations of IRI, PD173074, or both compounds for 72 hours before being lysed for determination of caspase 3 activity. Activity was calculated relative to the untreated control, and bars represent the mean ± SD of three independent experiments. Differences were analyzed by Student's t test with Welch correction. (A) SW480 control, (B) SW480 FGFR3-IIIc, (C) Caco-2, and (D) SW620 control.

    Journal: Translational Oncology

    Article Title: Irinotecan Upregulates Fibroblast Growth Factor Receptor 3 Expression in Colorectal Cancer Cells, Which Mitigates Irinotecan-Induced Apoptosis 1 2

    doi: 10.1016/j.tranon.2017.02.004

    Figure Lengend Snippet: IRI-induced caspase activity. Cells were exposed to synergistic concentrations of IRI, PD173074, or both compounds for 72 hours before being lysed for determination of caspase 3 activity. Activity was calculated relative to the untreated control, and bars represent the mean ± SD of three independent experiments. Differences were analyzed by Student's t test with Welch correction. (A) SW480 control, (B) SW480 FGFR3-IIIc, (C) Caco-2, and (D) SW620 control.

    Article Snippet: Shortly, protein was isolated from cells by homogenization in lysate buffer, and enzyme activity was measured by incubation with the specific fluorescent caspase substrate (sc-311,274, Santa Cruz Biotech) for 90 minutes.

    Techniques: Activity Assay, Control